{"id":74958,"date":"2026-04-27T12:20:25","date_gmt":"2026-04-27T04:20:25","guid":{"rendered":"http:\/\/111.62.156.167\/?chemical-product=s-naproxen-acyl-b-d-glucuronide"},"modified":"2026-04-27T12:20:25","modified_gmt":"2026-04-27T04:20:25","slug":"s-naproxen-acyl-b-d-glucuronide","status":"publish","type":"chemical-product","link":"https:\/\/bio-get.com\/?chemical-product=s-naproxen-acyl-b-d-glucuronide","title":{"rendered":"(S)-Naproxen acyl-b-D-glucuronide"},"content":{"rendered":"

\u4ea7\u54c1\u8bf4\u660e
\n\u4ea7\u54c1\u8bf4\u660e
\n1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n(S)-Naproxen acyl-\u03b2-D-glucuronide\uff08\u4ea7\u54c1\u76ee\u5f55\u53f7\uff1aBGGCB-5609\uff0cCAS\u53f7\uff1a41945-43-1\uff09\u662f\u4e00\u79cd\u8418\u666e\u751f\u7684\u8461\u8404\u7cd6\u919b\u9178\u7ed3\u5408\u4ee3\u8c22\u7269\uff0c\u5206\u5b50\u5f0f\u4e3aC20H22O9\uff0c\u5206\u5b50\u91cf\u4e3a406.38 g\/mol\u3002\u8be5\u5316\u5408\u7269\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7c89\u672b\uff0c\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u5177\u6709\u8f83\u9ad8\u7684\u5316\u5b66\u7a33\u5b9a\u6027\u548c\u6c34\u6eb6\u6027\u3002\u5176\u7ed3\u6784\u4e2d\u7684\u8461\u8404\u7cd6\u919b\u9178\u57fa\u56e2\u901a\u8fc7\u9170\u57fa\u952e\u4e0e(S)-\u8418\u666e\u751f\u7ed3\u5408\uff0c\u662f\u836f\u7269\u4ee3\u8c22\u7814\u7a76\u4e2d\u7684\u91cd\u8981\u53c2\u8003\u6807\u51c6\u54c1\u3002
\n2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n(S)-Naproxen acyl-\u03b2-D-glucuronide\u662f\u8418\u666e\u751f\u5728\u4eba\u4f53\u5185\u901a\u8fc7UDP-\u8461\u8404\u7cd6\u919b\u9178\u8f6c\u79fb\u9176\uff08UGT\uff09\u50ac\u5316\u751f\u6210\u7684\u4e3b\u8981\u4ee3\u8c22\u4ea7\u7269\u4e4b\u4e00\u3002\u5176\u5f62\u6210\u662f\u836f\u7269\u2161\u76f8\u4ee3\u8c22\u7684\u5178\u578b\u9014\u5f84\uff0c\u6709\u52a9\u4e8e\u63d0\u9ad8\u836f\u7269\u7684\u6c34\u6eb6\u6027\u5e76\u4fc3\u8fdb\u6392\u6cc4\u3002\u8be5\u4ee3\u8c22\u7269\u7684\u7814\u7a76\u5bf9\u4e8e\u7406\u89e3\u8418\u666e\u751f\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u3001\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u4ee5\u53ca\u4e2a\u4f53\u4ee3\u8c22\u5dee\u5f02\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002
\n3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n– \u836f\u7269\u4ee3\u8c22\u7814\u7a76\uff1a\u4f5c\u4e3a\u8418\u666e\u751f\u4ee3\u8c22\u7684\u6807\u8bb0\u7269\uff0c\u7528\u4e8e\u4f53\u5916\u548c\u4f53\u5185\u4ee3\u8c22\u5b9e\u9a8c\u3002
\n– \u5206\u6790\u6807\u51c6\u54c1\uff1a\u7528\u4e8eHPLC\u3001LC-MS\u7b49\u5206\u6790\u65b9\u6cd5\u4e2d\u4f5c\u4e3a\u5b9a\u91cf\u6216\u5b9a\u6027\u53c2\u8003\u7269\u8d28\u3002
\n– \u6bd2\u7406\u5b66\u7814\u7a76\uff1a\u8bc4\u4f30\u8418\u666e\u751f\u53ca\u5176\u4ee3\u8c22\u7269\u7684\u6f5c\u5728\u6bd2\u6027\u6216\u751f\u7269\u6d3b\u6027\u3002
\n– \u9176\u5b66\u7814\u7a76\uff1a\u7528\u4e8eUGT\u9176\u6d3b\u6027\u548c\u6291\u5236\u5b9e\u9a8c\u7684\u5e95\u7269\u6216\u4ea7\u7269\u3002
\n4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n– \u50a8\u5b58\u6761\u4ef6\uff1a\u5efa\u8bae\u5728-20\u00b0C\u4e0b\u907f\u5149\u5e72\u71e5\u4fdd\u5b58\uff0c\u957f\u671f\u50a8\u5b58\u53ef\u7f6e\u4e8e-80\u00b0C\u3002
\n– \u6eb6\u89e3\u6027\uff1a\u53ef\u6eb6\u4e8e\u7532\u9187\u3001DMSO\u6216\u6c34\uff08\u9700\u8d85\u58f0\u8f85\u52a9\u6eb6\u89e3\uff09\u3002
\n– \u4f7f\u7528\u5efa\u8bae\uff1a\u4f7f\u7528\u524d\u6062\u590d\u81f3\u5ba4\u6e29\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u5b9e\u9a8c\u65f6\u9700\u4f69\u6234\u9632\u62a4\u8bbe\u5907\uff0c\u5e76\u5728\u901a\u98ce\u6a71\u4e2d\u64cd\u4f5c\u3002
\n5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n– \u8d28\u91cf\u63a7\u5236\uff1a\u901a\u8fc7HPLC\u548c\u8d28\u8c31\u5206\u6790\u786e\u4fdd\u7eaf\u5ea6>96%\uff0c\u5e76\u63d0\u4f9bCOA\uff08\u8d28\u91cf\u5206\u6790\u8bc1\u4e66\uff09\u3002
\n– \u5b89\u5168\u4fe1\u606f\uff1a\u672c\u54c1\u53ef\u80fd\u5bf9\u773c\u775b\u3001\u76ae\u80a4\u548c\u547c\u5438\u9053\u6709\u523a\u6fc0\u6027\uff0c\u64cd\u4f5c\u65f6\u9700\u7a7f\u6234\u5b9e\u9a8c\u670d\u3001\u624b\u5957\u548c\u62a4\u76ee\u955c\u3002\u5982\u63a5\u89e6\u76ae\u80a4\u6216\u773c\u775b\uff0c\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002\u5e9f\u5f03\u7269\u9700\u6309\u5371\u9669\u5316\u5b66\u54c1\u89c4\u8303\u5904\u7f6e\u3002
\n\u672c\u4ea7\u54c1\u4ec5\u4f9b\u79d1\u7814\u4f7f\u7528\uff0c\u4e0d\u53ef\u7528\u4e8e\u4e34\u5e8a\u8bca\u65ad\u6216\u6cbb\u7597\u3002<\/p>\n","protected":false},"featured_media":57930,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[31],"class_list":["post-74958","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-31"],"acf":[],"taxonomy_info":{"product_category":[{"value":31,"label":"\u7cd6\u79d1\u5b66"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/41945-43-1_processed.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/74958","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/57930"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=74958"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=74958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}