{"id":72444,"date":"2026-04-27T11:42:28","date_gmt":"2026-04-27T03:42:28","guid":{"rendered":"http:\/\/111.62.156.167\/?chemical-product=4-hydroxypropanolol-d-glucuronide-d5"},"modified":"2026-04-27T11:42:28","modified_gmt":"2026-04-27T03:42:28","slug":"4-hydroxypropanolol-d-glucuronide-d5","status":"publish","type":"chemical-product","link":"https:\/\/bio-get.com\/?chemical-product=4-hydroxypropanolol-d-glucuronide-d5","title":{"rendered":"4′-Hydroxypropanolol D-glucuronide D5"},"content":{"rendered":"

\u4ea7\u54c1\u8bf4\u660e
\n4\u2032-\u7f9f\u57fa\u666e\u8418\u6d1b\u5c14D-\u8461\u8404\u7cd6\u919b\u9178\u82f7D5\u4ea7\u54c1\u8bf4\u660e\u4e66
\n1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u672c\u4ea7\u54c1\u4e3a\u6c18\u4ee3\u6807\u8bb0\u5316\u5408\u7269\uff0c\u5316\u5b66\u540d\u79f0\u4e3a4\u2032-Hydroxypropanolol D-glucuronide D5\uff0c\u662f\u4e00\u79cd\u9ad8\u7eaf\u5ea6\u751f\u5316\u8bd5\u5242\u3002\u5176\u5206\u5b50\u5f0f\u4e3aC22H24NO9D5\uff0c\u5206\u5b50\u91cf456.51 g\/mol\uff0c\u6c18\u4ee3\u4f4d\u7f6e\u5206\u5e03\u4e8e\u8461\u8404\u7cd6\u919b\u9178\u57fa\u56e2\uff0c\u6807\u8bb0\u7eaf\u5ea6>96%\u3002\u8be5\u5316\u5408\u7269\u662f\u666e\u8418\u6d1b\u5c14\uff08\u03b2-\u53d7\u4f53\u963b\u6ede\u5242\uff09\u7684\u4e3b\u8981\u4ee3\u8c22\u4ea7\u7269\u4e4b\u4e00\uff0c\u7ecf\u809d\u810fUGT\u9176\u50ac\u5316\u540e\u5f62\u6210\uff0c\u5177\u6709\u5178\u578b\u7684\u4e24\u4eb2\u6027\u7ed3\u6784\u7279\u5f81\uff0c\u53ef\u6eb6\u4e8e\u7532\u9187\u3001\u4e59\u8148\u7b49\u6709\u673a\u6eb6\u5242\uff0c\u6c34\u6eb6\u6027\u4e2d\u7b49\u3002
\n2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u666e\u8418\u6d1b\u5c14\u7684\u8461\u8404\u7cd6\u919b\u9178\u7ed3\u5408\u4ee3\u8c22\u7269\uff0c\u672c\u4ea7\u54c1\u5728\u836f\u7269\u4ee3\u8c22\u7814\u7a76\u4e2d\u5177\u6709\u5173\u952e\u4f5c\u7528\u3002\u5176\u6c18\u4ee3\u6807\u8bb0\u7279\u6027\uff08D5\uff09\u53ef\u663e\u8457\u964d\u4f4e\u8d28\u8c31\u5206\u6790\u4e2d\u7684\u80cc\u666f\u5e72\u6270\uff0c\u9002\u7528\u4e8e\u540c\u4f4d\u7d20\u7a00\u91ca\u8d28\u8c31\u6cd5\uff08IDMS\uff09\u7b49\u5b9a\u91cf\u5206\u6790\u6280\u672f\u3002\u8be5\u4ee3\u8c22\u7269\u5728\u4f53\u5185\u53cd\u6620UGT1A9\u548cUGT2B7\u7b49\u9176\u7684\u6d3b\u6027\uff0c\u662f\u7814\u7a76\u836f\u7269-\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u3001\u4ee3\u8c22\u901a\u8def\u53ca\u4e2a\u4f53\u5316\u7528\u836f\u7684\u91cd\u8981\u751f\u7269\u6807\u5fd7\u7269\u3002
\n3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u672c\u4ea7\u54c1\u4e3b\u8981\u7528\u4e8e\u4ee5\u4e0b\u9886\u57df\uff1a\u836f\u7269\u4ee3\u8c22\u52a8\u529b\u5b66\u7814\u7a76\uff08\u5982\u4f53\u5916\/\u4f53\u5185\u4ee3\u8c22\u7a33\u5b9a\u6027\u5b9e\u9a8c\uff09\u3001\u4e34\u5e8a\u6bd2\u7406\u5b66\u5206\u6790\uff08\u5982\u8fc7\u91cf\u7528\u836f\u76d1\u6d4b\uff09\u3001\u9176\u52a8\u529b\u5b66\u6a21\u578b\u6784\u5efa\u3002\u5177\u4f53\u5e94\u7528\u4e8e\uff1a
\n– LC-MS\/MS\u6cd5\u5efa\u7acb\u666e\u8418\u6d1b\u5c14\u4ee3\u8c22\u5b9a\u91cf\u6807\u51c6\u66f2\u7ebf
\n– \u6c18\u4ee3\u5185\u6807\u7269\u7528\u4e8e\u8840\u6d46\/\u5c3f\u6db2\u6837\u672c\u7684\u7cbe\u51c6\u5b9a\u91cf
\n– UGT\u9176\u4e9a\u578b\u7279\u5f02\u6027\u7814\u7a76\u4e2d\u7684\u6807\u51c6\u53c2\u7167\u7269
\n4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u50a8\u5b58\u4e8e-20\u2103\u907f\u5149\u5e72\u71e5\u73af\u5883\uff0c\u5f00\u5c01\u540e\u5efa\u8bae\u5206\u88c5\u4fdd\u5b58\u4ee5\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u4f7f\u7528\u524d\u9700\u5e73\u8861\u81f3\u5ba4\u6e29\uff0c\u77ed\u6682\u79bb\u5fc3\u786e\u4fdd\u7c89\u672b\u805a\u96c6\u3002\u63a8\u8350\u7528\u7532\u9187\u914d\u523610 mM\u6bcd\u6db2\uff0c-80\u2103\u4fdd\u5b58\u4e0d\u8d85\u8fc76\u4e2a\u6708\u3002\u5de5\u4f5c\u6db2\u9700\u73b0\u914d\u73b0\u7528\uff0c\u907f\u514d\u9178\u6027\u6761\u4ef6\uff08pH<5\uff09\u5bfc\u81f4\u7cd6\u82f7\u952e\u6c34\u89e3\u3002\n5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f \n\u672c\u54c1\u7ecfHPLC-UV\u53caLC-MS\u53cc\u91cd\u9a8c\u8bc1\uff0c\u5316\u5b66\u7eaf\u5ea6>96%\uff0c\u540c\u4f4d\u7d20\u4e30\u5ea6>98%\uff08D5\uff09\u3002\u4f7f\u7528\u65f6\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u53ca\u62a4\u76ee\u955c\uff0c\u907f\u514d\u5438\u5165\u7c89\u5c18\u3002MSDS\u6570\u636e\u663e\u793a\u5176\u6025\u6027\u6bd2\u6027\u8f83\u4f4e\uff08LD50>2000 mg\/kg\uff09\uff0c\u4f46\u53ef\u80fd\u5bf9\u773c\u775b\u53ca\u547c\u5438\u9053\u4ea7\u751f\u8f7b\u5fae\u523a\u6fc0\u3002\u5e9f\u5f03\u7269\u5904\u7f6e\u9700\u7b26\u5408\u6709\u673a\u6eb6\u5242\u7ba1\u7406\u89c4\u8303\u3002
\n\u6ce8\uff1aCAS\u53f7\u56e0\u5546\u4e1a\u4fdd\u5bc6\u8981\u6c42\u6682\u4e0d\u516c\u5f00\uff0c\u5177\u4f53\u6280\u672f\u53c2\u6570\u53ef\u7d22\u53d6COA\u62a5\u544a\u3002<\/p>\n","protected":false},"featured_media":59445,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[31],"class_list":["post-72444","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-31"],"acf":[],"taxonomy_info":{"product_category":[{"value":31,"label":"\u7cd6\u79d1\u5b66"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/BGGCB-0136_processed.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/72444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/59445"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=72444"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=72444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}