{"id":69699,"date":"2026-04-27T11:10:00","date_gmt":"2026-04-27T03:10:00","guid":{"rendered":"http:\/\/111.62.156.167\/?chemical-product=levofloxacin-acyl-b-d-glucuronide"},"modified":"2026-04-27T11:10:00","modified_gmt":"2026-04-27T03:10:00","slug":"levofloxacin-acyl-b-d-glucuronide","status":"publish","type":"chemical-product","link":"https:\/\/bio-get.com\/?chemical-product=levofloxacin-acyl-b-d-glucuronide","title":{"rendered":"Levofloxacin acyl-b-D-glucuronide"},"content":{"rendered":"<p>\u4ea7\u54c1\u8bf4\u660e<br \/>\n1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027<br \/>\n\u672c\u54c1\u4e3a\u5de6\u6c27\u6c1f\u6c99\u661f\u9170\u57fa-\u03b2-D-\u8461\u8404\u7cd6\u919b\u9178\u82f7\uff08Levofloxacin acyl-\u03b2-D-glucuronide\uff09\uff0c\u5316\u5b66\u540d\u79f0\u7b26\u5408IUPAC\u547d\u540d\u89c4\u8303\uff0cCAS\u6ce8\u518c\u53f7160962-46-9\uff0c\u5206\u5b50\u5f0fC24H28FN3O10\uff0c\u5206\u5b50\u91cf537.49 g\/mol\u3002\u4ea7\u54c1\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7ed3\u6676\u6027\u7c89\u672b\uff0c\u7eaf\u5ea6\u7ecfHPLC\u9a8c\u8bc1\u226596%\uff0c\u5177\u6709\u5178\u578b\u8461\u8404\u7cd6\u919b\u9178\u82f7\u952e\u7684\u7d2b\u5916\u5438\u6536\u7279\u5f81\uff08\u03bbmax 290-300 nm\uff09\u3002\u5176\u7ed3\u6784\u5305\u542b\u5de6\u6c27\u6c1f\u6c99\u661f\u6bcd\u6838\u4e0e\u8461\u8404\u7cd6\u919b\u9178\u901a\u8fc7\u9170\u57fa\u03b2-\u7cd6\u82f7\u952e\u7ed3\u5408\uff0c\u6c34\u6eb6\u6027\u8f83\u6bcd\u4f53\u836f\u7269\u663e\u8457\u63d0\u9ad8\uff0c\u5728pH 7.4\u78f7\u9178\u7f13\u51b2\u6db2\u4e2d\u6eb6\u89e3\u5ea6\u4e3a25 mg\/mL\u3002<br \/>\n2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027<br \/>\n\u4f5c\u4e3a\u5de6\u6c27\u6c1f\u6c99\u661f\u7684\u4e3b\u8981\u2161\u76f8\u4ee3\u8c22\u4ea7\u7269\uff0c\u672c\u54c1\u5728\u836f\u7269\u4ee3\u8c22\u7814\u7a76\u4e2d\u5177\u6709\u5173\u952e\u4ef7\u503c\u3002\u5176\u5f62\u6210\u4f9d\u8d56\u4e8eUGT1A1\/1A3\u9176\u4ecb\u5bfc\u7684\u8461\u8404\u7cd6\u919b\u9178\u5316\u53cd\u5e94\uff0c\u662f\u8bc4\u4f30\u809d\u836f\u9176\u6d3b\u6027\u548c\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7684\u91cd\u8981\u751f\u7269\u6807\u5fd7\u7269\u3002\u4f53\u5916\u7814\u7a76\u8868\u660e\uff0c\u8be5\u4ee3\u8c22\u4ea7\u7269\u6297\u83cc\u6d3b\u6027\u8f83\u539f\u578b\u836f\u7269\u964d\u4f4e\u7ea68-10\u500d\uff0c\u4f46\u53ef\u901a\u8fc7\u80a0\u9053\u83cc\u7fa4\u03b2-\u8461\u8404\u7cd6\u919b\u9178\u82f7\u9176\u518d\u751f\u4e3a\u6d3b\u6027\u6bcd\u4f53\uff0c\u53c2\u4e0e\u80a0\u809d\u5faa\u73af\u8fc7\u7a0b\u3002<br \/>\n3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014<br \/>\n\u672c\u4ea7\u54c1\u4e13\u4e3a\u4ee5\u4e0b\u7814\u7a76\u8bbe\u8ba1\uff1a<br \/>\n(1) \u836f\u7269\u4ee3\u8c22\u52a8\u529b\u5b66\u7814\u7a76\uff1a\u4f5c\u4e3aHPLC\/MS\u5b9a\u91cf\u5206\u6790\u7684\u53c2\u6bd4\u6807\u51c6\u54c1<br \/>\n(2) \u4f53\u5916\u4ee3\u8c22\u6a21\u578b\u9a8c\u8bc1\uff1a\u7528\u4e8e\u809d\u5fae\u7c92\u4f53\/\u539f\u4ee3\u809d\u7ec6\u80deUGT\u9176\u6d3b\u6027\u6d4b\u5b9a<br \/>\n(3) \u836f\u7269-\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7814\u7a76\uff1a\u8bc4\u4f30UGT\u9176\u6291\u5236\u5242\u6216\u8bf1\u5bfc\u5242\u7684\u5f71\u54cd<br \/>\n(4) \u4e34\u5e8a\u6bd2\u7406\u5b66\u7814\u7a76\uff1a\u68c0\u6d4b\u60a3\u8005\u6837\u672c\u4e2d\u4ee3\u8c22\u7269\u79ef\u7d2f\u60c5\u51b5<br \/>\n4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae<br \/>\n\u957f\u671f\u50a8\u5b58\u9700\u7f6e\u4e8e-20\u2103\u5e72\u71e5\u907f\u5149\u73af\u5883\uff0c\u5f00\u5c01\u540e\u5efa\u8bae\u5206\u88c5\u4fdd\u5b58\u4e8e\u60f0\u6027\u6c14\u4f53\uff08\u5982\u6c29\u6c14\uff09\u4fdd\u62a4\u7684\u5bc6\u5c01\u74f6\u4e2d\u3002\u5de5\u4f5c\u6eb6\u6db2\u9700\u73b0\u914d\u73b0\u7528\uff0c\u82e5\u9700\u4fdd\u5b58\u5e94\u7f6e\u4e8e-80\u2103\uff08\u6709\u6548\u671f7\u5929\uff09\u3002\u6eb6\u89e3\u63a8\u8350\u4f7f\u7528\u9884\u51b7\u7684\u7532\u9187-\u6c34\uff081:1 v\/v\uff09\u6df7\u5408\u6eb6\u5242\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u5b9e\u9a8c\u64cd\u4f5c\u5efa\u8bae\u5728\u751f\u7269\u5b89\u5168\u67dc\u4e2d\u8fdb\u884c\uff0c\u4f69\u6234Nitrile\u624b\u5957\u53ca\u62a4\u76ee\u955c\u3002<br \/>\n5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f<br \/>\n\u6bcf\u6279\u6b21\u4ea7\u54c1\u5747\u63d0\u4f9bCOA\uff08\u8d28\u91cf\u5206\u6790\u8bc1\u4e66\uff09\uff0c\u5305\u542bHPLC\u7eaf\u5ea6\u56fe\u8c31\u3001LC-MS\u5206\u5b50\u91cf\u9a8c\u8bc1\u53ca\u6c34\u5206\u542b\u91cf\uff08KF\u6cd5\uff09\u6570\u636e\u3002\u6839\u636eGHS\u5206\u7c7b\uff0c\u672c\u54c1\u5c5e\u4e8e\u523a\u6fc0\u6027\u7269\u8d28\uff08Category 2\uff09\uff0c\u64cd\u4f5c\u65f6\u9700\u907f\u514d\u5438\u5165\u7c89\u5c18\u6216\u63a5\u89e6\u76ae\u80a4\u3002\u5e9f\u5f03\u7269\u5904\u7f6e\u5e94\u53c2\u7167\u5f53\u5730\u5371\u9669\u5316\u5b66\u54c1\u7ba1\u7406\u6761\u4f8b\uff0c\u5efa\u8bae\u91c7\u752810%\u6c22\u6c27\u5316\u94a0\u6eb6\u6db2\u964d\u89e3\u5904\u7406\u540e\u4ea4\u7531\u4e13\u4e1a\u673a\u6784\u5904\u7406\u3002\u6025\u6551\u63aa\u65bd\uff1a\u773c\u90e8\u63a5\u89e6\u7acb\u5373\u7528\u751f\u7406\u76d0\u6c34\u51b2\u6d1715\u5206\u949f\uff0c\u76ae\u80a4\u63a5\u89e6\u540e\u7528\u80a5\u7682\u6c34\u5f7b\u5e95\u6e05\u6d17\u3002<\/p>\n","protected":false},"featured_media":56772,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[31],"class_list":["post-69699","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-31"],"acf":[],"taxonomy_info":{"product_category":[{"value":31,"label":"\u7cd6\u79d1\u5b66"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/160962-46-9_processed.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/69699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/56772"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=69699"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=69699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}