\u4ea7\u54c1\u8bf4\u660e <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n(2-(\u4e59\u6c27\u57fa\u7fb0\u57fa)\u73af\u4e19\u57fa)\u4e09\u6c1f\u787c\u9178\u94be\uff08\u5316\u5b66\u540d\u79f0\uff1apotassium rac-((1R,2R)-2-(ethoxycarbonyl)cyclopropyl)trifluoroborate\uff09\u662f\u4e00\u79cd\u6709\u673a\u787c\u9178\u76d0\u5316\u5408\u7269\uff0cCAS\u53f7\u4e3a1612792-88-7\uff0c\u5206\u5b50\u5f0f\u4e3aC6H9BF3KO2\uff0c\u5206\u5b50\u91cf\u4e3a220.04\u3002\u8be5\u5316\u5408\u7269\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u56fa\u4f53\uff0c\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u5177\u6709\u826f\u597d\u7684\u6eb6\u89e3\u6027\u548c\u7a33\u5b9a\u6027\uff0c\u9002\u7528\u4e8e\u591a\u79cd\u6709\u673a\u5408\u6210\u53cd\u5e94\u3002\u5176\u7ed3\u6784\u4e2d\u5305\u542b\u73af\u4e19\u57fa\u548c\u4e09\u6c1f\u787c\u9178\u57fa\u56e2\uff0c\u4f7f\u5176\u5728\u8fc7\u6e21\u91d1\u5c5e\u50ac\u5316\u53cd\u5e94\u4e2d\u8868\u73b0\u51fa\u4f18\u5f02\u7684\u53cd\u5e94\u6d3b\u6027\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u8be5\u5316\u5408\u7269\u4f5c\u4e3a\u6709\u673a\u787c\u9178\u884d\u751f\u7269\uff0c\u5728Suzuki-Miyaura\u5076\u8054\u53cd\u5e94\u4e2d\u5177\u6709\u91cd\u8981\u4f5c\u7528\u3002\u5176\u4e09\u6c1f\u787c\u9178\u57fa\u56e2\u80fd\u591f\u4e0e\u94af\u50ac\u5316\u5242\u5f62\u6210\u7a33\u5b9a\u7684\u4e2d\u95f4\u4f53\uff0c\u4fc3\u8fdb\u78b3-\u78b3\u952e\u7684\u5f62\u6210\uff0c\u5e7f\u6cdb\u5e94\u7528\u4e8e\u590d\u6742\u5206\u5b50\u7684\u6784\u5efa\u3002\u6b64\u5916\uff0c\u73af\u4e19\u57fa\u7ed3\u6784\u7684\u5f15\u5165\u53ef\u589e\u5f3a\u5316\u5408\u7269\u7684\u7acb\u4f53\u9009\u62e9\u6027\uff0c\u4e3a\u836f\u7269\u5206\u5b50\u548c\u529f\u80fd\u6750\u6599\u7684\u5408\u6210\u63d0\u4f9b\u91cd\u8981\u4e2d\u95f4\u4f53\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n(2-(\u4e59\u6c27\u57fa\u7fb0\u57fa)\u73af\u4e19\u57fa)\u4e09\u6c1f\u787c\u9178\u94be\u4e3b\u8981\u7528\u4e8e\u533b\u836f\u7814\u53d1\u3001\u6750\u6599\u79d1\u5b66\u548c\u7cbe\u7ec6\u5316\u5de5\u9886\u57df\u3002\u5728\u836f\u7269\u5316\u5b66\u4e2d\uff0c\u5b83\u662f\u5408\u6210\u73af\u4e19\u57fa\u7c7b\u836f\u7269\u7684\u5173\u952e\u4e2d\u95f4\u4f53\uff0c\u53ef\u7528\u4e8e\u6297\u75c5\u6bd2\u3001\u6297\u80bf\u7624\u7b49\u6d3b\u6027\u5206\u5b50\u7684\u5236\u5907\u3002\u5728\u6750\u6599\u79d1\u5b66\u4e2d\uff0c\u8be5\u5316\u5408\u7269\u53ef\u7528\u4e8e\u529f\u80fd\u9ad8\u5206\u5b50\u6750\u6599\u7684\u4fee\u9970\u4e0e\u5408\u6210\u3002\u6b64\u5916\uff0c\u5b83\u8fd8\u5e38\u7528\u4e8e\u5b66\u672f\u7814\u7a76\u4e2d\u7684\u6709\u673a\u5408\u6210\u65b9\u6cd5\u5b66\u5f00\u53d1\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u8be5\u4ea7\u54c1\u9700\u5bc6\u5c01\u4fdd\u5b58\u4e8e\u5e72\u71e5\u3001\u9634\u51c9\u7684\u73af\u5883\u4e2d\uff0c\u907f\u514d\u4e0e\u6e7f\u6c14\u548c\u5f3a\u6c27\u5316\u5242\u63a5\u89e6\u3002\u63a8\u8350\u50a8\u5b58\u6e29\u5ea6\u4e3a2-8\u2103\uff0c\u957f\u671f\u4fdd\u5b58\u5efa\u8bae\u7f6e\u4e8e\u60f0\u6027\u6c14\u4f53\u4fdd\u62a4\u4e0b\u3002\u4f7f\u7528\u65f6\u5e94\u4f69\u6234\u9632\u62a4\u624b\u5957\u548c\u62a4\u76ee\u955c\uff0c\u5728\u901a\u98ce\u826f\u597d\u7684\u73af\u5883\u4e0b\u64cd\u4f5c\u3002\u6eb6\u89e3\u65f6\u5efa\u8bae\u4f7f\u7528\u65e0\u6c34\u6709\u673a\u6eb6\u5242\uff08\u5982\u4e8c\u7532\u57fa\u4e9a\u781c\u6216\u56db\u6c22\u544b\u5583\uff09\uff0c\u4ee5\u786e\u4fdd\u7a33\u5b9a\u6027\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
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