\u4ea7\u54c1\u540d\u79f0\uff1a3-((2-\u6c2f\u5627\u5576-4-\u57fa)\u6c27\u57fa)\u6c2e\u6742\u73af\u4e01\u70f7-1-\u7fa7\u9178\u53d4\u4e01\u916f
\n\u5316\u5b66\u540d\u79f0\uff1atert-butyl 3-(2-chloropyrimidin-4-yloxy)azetidine-1-carboxylate
\nCAS\u53f7\uff1a1121633-27-9
\n\u5206\u5b50\u5f0f\uff1aC12H16ClN3O3
\n\u5206\u5b50\u91cf\uff1a285.73
\n\u7eaf\u5ea6\uff1a>96% <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u672c\u54c1\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7ed3\u6676\u6027\u7c89\u672b\uff0c\u662f\u4e00\u79cd\u542b\u6c2e\u6742\u73af\u5316\u5408\u7269\uff0c\u5177\u6709\u5627\u5576\u73af\u548c\u6c2e\u6742\u73af\u4e01\u70f7\u7ed3\u6784\u3002\u5176\u5206\u5b50\u7ed3\u6784\u4e2d\u5305\u542b\u6c2f\u539f\u5b50\u548c\u53d4\u4e01\u6c27\u7fb0\u57fa\uff08Boc\uff09\u4fdd\u62a4\u57fa\uff0c\u8d4b\u4e88\u5176\u826f\u597d\u7684\u53cd\u5e94\u6d3b\u6027\u4e0e\u7a33\u5b9a\u6027\u3002\u8be5\u5316\u5408\u7269\u6613\u6eb6\u4e8e\u6709\u673a\u6eb6\u5242\u5982\u4e8c\u7532\u57fa\u4e9a\u781c\uff08DMSO\uff09\u3001\u7532\u9187\u548c\u4e59\u8148\uff0c\u4f46\u5728\u6c34\u4e2d\u6eb6\u89e3\u5ea6\u8f83\u4f4e\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u5627\u5576\u884d\u751f\u7269\uff0c\u8be5\u5316\u5408\u7269\u5728\u836f\u7269\u5316\u5b66\u548c\u6709\u673a\u5408\u6210\u4e2d\u5177\u6709\u91cd\u8981\u4ef7\u503c\u3002\u5176\u5627\u5576\u73af\u53ef\u4f5c\u4e3a\u6c22\u952e\u53d7\u4f53\u6216\u4f9b\u4f53\u53c2\u4e0e\u5206\u5b50\u95f4\u76f8\u4e92\u4f5c\u7528\uff0c\u800c\u6c2f\u539f\u5b50\u4e3a\u540e\u7eed\u4eb2\u6838\u53d6\u4ee3\u53cd\u5e94\u63d0\u4f9b\u4e86\u6d3b\u6027\u4f4d\u70b9\u3002Boc\u4fdd\u62a4\u57fa\u7684\u5b58\u5728\u4f7f\u5176\u5728\u56fa\u76f8\u5408\u6210\u548c\u591a\u80bd\u4fee\u9970\u4e2d\u5177\u6709\u5e7f\u6cdb\u5e94\u7528\u6f5c\u529b\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u672c\u54c1\u4e3b\u8981\u7528\u4e8e\u533b\u836f\u4e2d\u95f4\u4f53\u5408\u6210\uff0c\u7279\u522b\u662f\u5728\u6fc0\u9176\u6291\u5236\u5242\u548c\u6297\u80bf\u7624\u836f\u7269\u7684\u7814\u53d1\u4e2d\u3002\u5176\u53ef\u4f5c\u4e3a\u5173\u952e\u9aa8\u67b6\u7528\u4e8e\u6784\u5efaEGFR\u3001CDK\u7b49\u9776\u70b9\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\u3002\u6b64\u5916\uff0c\u5728\u519c\u836f\u5316\u5b66\u9886\u57df\uff0c\u8be5\u5316\u5408\u7269\u4e5f\u53ef\u7528\u4e8e\u65b0\u578b\u6740\u866b\u5242\u6216\u6740\u83cc\u5242\u7684\u524d\u4f53\u5408\u6210\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u5efa\u8bae\u5728-20\u00b0C\u4e0b\u907f\u5149\u5e72\u71e5\u50a8\u5b58\uff0c\u957f\u671f\u4fdd\u5b58\u9700\u5145\u60f0\u6027\u6c14\u4f53\u4fdd\u62a4\u3002\u4f7f\u7528\u524d\u9700\u6062\u590d\u81f3\u5ba4\u6e29\u5e76\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u64cd\u4f5c\u65f6\u5e94\u5728\u901a\u98ce\u6a71\u4e2d\u8fdb\u884c\uff0c\u4f69\u6234\u9632\u62a4\u624b\u5957\u548c\u62a4\u76ee\u955c\u3002\u6eb6\u89e3\u5efa\u8bae\u4f7f\u7528\u65e0\u6c34\u7ea7\u6709\u673a\u6eb6\u5242\uff0c\u5e76\u907f\u514d\u4e0e\u5f3a\u6c27\u5316\u5242\u63a5\u89e6\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u672c\u54c1\u901a\u8fc7HPLC\u68c0\u6d4b\u7eaf\u5ea6>96%\uff0c\u5e76\u63d0\u4f9b\u5b8c\u6574\u7684COA\uff08\u8d28\u91cf\u5206\u6790\u8bc1\u4e66\uff09\u3002\u5176\u6025\u6027\u6bd2\u6027\u6570\u636e\u4e3aLD50>500 mg\/kg\uff08\u5927\u9f20\uff0c\u53e3\u670d\uff09\uff0c\u5c5e\u4e8e\u523a\u6fc0\u6027\u5316\u5b66\u54c1\u3002\u5982\u63a5\u89e6\u76ae\u80a4\u6216\u773c\u775b\uff0c\u5e94\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002\u5e9f\u5f03\u7269\u5904\u7406\u9700\u7b26\u5408\u5f53\u5730\u73af\u4fdd\u6cd5\u89c4\uff0c\u5efa\u8bae\u901a\u8fc7\u4e13\u4e1a\u5316\u5b66\u54c1\u56de\u6536\u673a\u6784\u5904\u7f6e\u3002 <\/p>\n
\u6ce8\uff1a\u672c\u4ea7\u54c1\u4ec5\u9650\u79d1\u7814\u7528\u9014\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u4f53\u6216\u52a8\u7269\u5b9e\u9a8c\u3002\u5177\u4f53\u5e94\u7528\u524d\u8bf7\u67e5\u9605\u6700\u65b0\u6587\u732e\u5e76\u5f00\u5c55\u5b89\u5168\u6027\u8bc4\u4f30\u3002<\/p>\n","protected":false},"featured_media":24297,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[25],"class_list":["post-55367","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-25"],"acf":[],"taxonomy_info":{"product_category":[{"value":25,"label":"\u5b9e\u9a8c\u836f\u54c1"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/1121633-27-9.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/55367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/24297"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55367"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=55367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}