{"id":55089,"date":"2026-04-16T17:43:23","date_gmt":"2026-04-16T09:43:23","guid":{"rendered":"http:\/\/111.62.156.167\/?chemical-product=alirocumab"},"modified":"2026-04-16T17:43:23","modified_gmt":"2026-04-16T09:43:23","slug":"alirocumab","status":"publish","type":"chemical-product","link":"https:\/\/bio-get.com\/?chemical-product=alirocumab","title":{"rendered":"Alirocumab"},"content":{"rendered":"

Alirocumab\u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n

1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\nAlirocumab\u662f\u4e00\u79cd\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u5316\u5b66\u540d\u79f0\u4e3aAlirocumab\uff0cCAS\u53f7\u4e3a1245916-14-6\u3002\u5176\u5206\u5b50\u7ed3\u6784\u7ecf\u8fc7\u57fa\u56e0\u5de5\u7a0b\u6280\u672f\u4f18\u5316\uff0c\u7279\u5f02\u6027\u9776\u5411PCSK9\uff08\u524d\u86cb\u767d\u8f6c\u5316\u9176\u67af\u8349\u6eb6\u83cc\u7d209\uff09\u86cb\u767d\u3002\u672c\u4ea7\u54c1\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u901a\u8fc7\u9ad8\u6548\u6db2\u76f8\u8272\u8c31\uff08HPLC\uff09\u9a8c\u8bc1\uff0c\u786e\u4fdd\u6279\u6b21\u95f4\u4e00\u81f4\u6027\u3002Alirocumab\u5728\u751f\u7406\u6761\u4ef6\u4e0b\u8868\u73b0\u51fa\u9ad8\u4eb2\u548c\u529b\u548c\u7a33\u5b9a\u6027\uff0c\u9002\u5408\u4f53\u5916\u53ca\u4f53\u5185\u7814\u7a76\u5e94\u7528\u3002 <\/p>\n

2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\nAlirocumab\u901a\u8fc7\u7ed3\u5408PCSK9\u86cb\u767d\uff0c\u963b\u65ad\u5176\u4e0e\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u53d7\u4f53\uff08LDLR\uff09\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u4ece\u800c\u51cf\u5c11LDLR\u7684\u964d\u89e3\uff0c\u589e\u5f3a\u809d\u810f\u5bf9\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\uff08LDL-C\uff09\u7684\u6e05\u9664\u80fd\u529b\u3002\u8fd9\u4e00\u673a\u5236\u5728\u8c03\u8282\u8840\u8102\u4ee3\u8c22\u4e2d\u5177\u6709\u5173\u952e\u4f5c\u7528\uff0c\u4e3a\u5fc3\u8840\u7ba1\u75be\u75c5\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u9776\u70b9\u3002Alirocumab\u7684\u7814\u53d1\u4ee3\u8868\u4e86\u964d\u8102\u7597\u6cd5\u4ece\u4f20\u7edf\u5c0f\u5206\u5b50\u836f\u7269\u5230\u751f\u7269\u5236\u5242\u7684\u91cd\u5927\u7a81\u7834\u3002 <\/p>\n

3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\nAlirocumab\u4e3b\u8981\u7528\u4e8e\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u7814\u7a76\u4e0e\u6cbb\u7597\uff0c\u5305\u62ec\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u548c\u52a8\u8109\u7ca5\u6837\u786c\u5316\u7684\u4e34\u5e8a\u524d\u53ca\u4e34\u5e8a\u7814\u7a76\u3002\u5728\u836f\u7269\u5f00\u53d1\u4e2d\uff0c\u5b83\u53ef\u4f5c\u4e3a\u9633\u6027\u5bf9\u7167\u6216\u5de5\u5177\u6297\u4f53\uff0c\u7528\u4e8e\u9a8c\u8bc1PCSK9\u6291\u5236\u5242\u7684\u836f\u6548\u5b66\u6a21\u578b\u3002\u6b64\u5916\uff0c\u5176\u4f5c\u7528\u673a\u5236\u7814\u7a76\u4e5f\u6709\u52a9\u4e8e\u63a2\u7d22\u8102\u4ee3\u8c22\u5f02\u5e38\u76f8\u5173\u75be\u75c5\u7684\u75c5\u7406\u673a\u5236\u3002 <\/p>\n

4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u672c\u4ea7\u54c1\u9700\u57282-8\u2103\u6761\u4ef6\u4e0b\u907f\u5149\u4fdd\u5b58\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u590d\u6eb6\u540e\u5efa\u8bae\u5206\u88c5\u4fdd\u5b58\u4e8e-20\u2103\uff0c\u5e76\u57286\u4e2a\u6708\u5185\u4f7f\u7528\u3002\u4f7f\u7528\u524d\u9700\u79bb\u5fc3\u53bb\u9664\u53ef\u80fd\u7684\u6c89\u6dc0\uff0c\u63a8\u8350\u5728\u65e0\u83cc\u6761\u4ef6\u4e0b\u64cd\u4f5c\u3002\u5b9e\u9a8c\u6d53\u5ea6\u9700\u6839\u636e\u5177\u4f53\u6a21\u578b\u4f18\u5316\uff0c\u5efa\u8bae\u521d\u59cb\u6d53\u5ea6\u4e3a0.1-10 \u03bcg\/mL\u8fdb\u884c\u5242\u91cf\u63a2\u7d22\u3002 <\/p>\n

5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u6bcf\u6279\u4ea7\u54c1\u5747\u901a\u8fc7SDS-PAGE\u548c\u8d28\u8c31\u5206\u6790\u9a8c\u8bc1\u7eaf\u5ea6\u4e0e\u5206\u5b50\u91cf\u3002\u5185\u6bd2\u7d20\u542b\u91cf\u4f4e\u4e8e1 EU\/mg\uff0c\u7b26\u5408\u751f\u7269\u5236\u54c1\u6807\u51c6\u3002\u64cd\u4f5c\u65f6\u9700\u7a7f\u6234\u9632\u62a4\u88c5\u5907\uff0c\u907f\u514d\u76f4\u63a5\u63a5\u89e6\u76ae\u80a4\u6216\u9ecf\u819c\u3002\u5982\u53d1\u751f\u610f\u5916\u66b4\u9732\uff0c\u8bf7\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002\u672c\u4ea7\u54c1\u4ec5\u9650\u79d1\u7814\u4f7f\u7528\uff0c\u4e0d\u53ef\u7528\u4e8e\u8bca\u65ad\u6216\u6cbb\u7597\u7528\u9014\u3002 <\/p>\n

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