1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\nE3\u8fde\u63a5\u9176Ligand-Linker\u5171\u8f6d\u72697\uff08E3 ligase Ligand-Linker Conjugates 7\uff09\u662f\u4e00\u79cd\u9ad8\u7eaf\u5ea6\u7684\u5c0f\u5206\u5b50\u5316\u5408\u7269\uff0c\u5316\u5b66\u540d\u79f0\u4e3aE3 ligase Ligand-Linker Conjugates 7\uff0cCAS\u53f7\u4e3a2064292-52-8\u3002\u5176\u5206\u5b50\u5f0f\u4e3aC\u2083\u2087H\u2084\u2080N\u2084O\u2088\uff0c\u5206\u5b50\u91cf\u4e3a700.29\u3002\u8be5\u5316\u5408\u7269\u7eaf\u5ea6\u8d85\u8fc796%\uff0c\u5177\u6709\u660e\u786e\u7684\u5316\u5b66\u7ed3\u6784\u548c\u7a33\u5b9a\u7684\u7406\u5316\u6027\u8d28\uff0c\u9002\u7528\u4e8e\u591a\u79cd\u751f\u7269\u5316\u5b66\u7814\u7a76\u573a\u666f\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\nE3\u8fde\u63a5\u9176Ligand-Linker\u5171\u8f6d\u72697\u662f\u4e00\u79cd\u5173\u952e\u7684\u86cb\u767d\u964d\u89e3\u9776\u5411\u5d4c\u5408\u4f53\uff08PROTAC\uff09\u5206\u5b50\u7ec4\u6210\u90e8\u5206\uff0c\u80fd\u591f\u7279\u5f02\u6027\u7ed3\u5408E3\u6cdb\u7d20\u8fde\u63a5\u9176\u3002\u901a\u8fc7Linker\u90e8\u5206\u4e0e\u9776\u86cb\u767d\u914d\u4f53\u8fde\u63a5\uff0c\u8be5\u5316\u5408\u7269\u53ef\u8bf1\u5bfc\u9776\u86cb\u767d\u7684\u6cdb\u7d20\u5316\u4fee\u9970\uff0c\u8fdb\u800c\u901a\u8fc7\u86cb\u767d\u9176\u4f53\u9014\u5f84\u964d\u89e3\u76ee\u6807\u86cb\u767d\u3002\u8fd9\u4e00\u673a\u5236\u5728\u8c03\u63a7\u86cb\u767d\u8d28\u7a33\u6001\u548c\u529f\u80fd\u7814\u7a76\u4e2d\u5177\u6709\u91cd\u8981\u610f\u4e49\uff0c\u5c24\u5176\u5728\u836f\u7269\u5f00\u53d1\u548c\u75be\u75c5\u673a\u5236\u7814\u7a76\u4e2d\u5907\u53d7\u5173\u6ce8\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u8be5\u5316\u5408\u7269\u5e7f\u6cdb\u5e94\u7528\u4e8ePROTAC\u6280\u672f\u9886\u57df\uff0c\u7528\u4e8e\u8bbe\u8ba1\u548c\u5f00\u53d1\u65b0\u578b\u9776\u5411\u86cb\u767d\u964d\u89e3\u836f\u7269\u3002\u5177\u4f53\u7528\u9014\u5305\u62ec\uff1a
\n– \u7528\u4e8e\u7814\u7a76\u7279\u5b9a\u86cb\u767d\u7684\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236
\n– \u4f5c\u4e3aPROTAC\u5206\u5b50\u7684\u6838\u5fc3\u7ec4\u4ef6\uff0c\u7528\u4e8e\u836f\u7269\u7b5b\u9009\u548c\u4f18\u5316
\n– \u5728\u764c\u75c7\u3001\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7b49\u9886\u57df\u7684\u5206\u5b50\u673a\u5236\u7814\u7a76\u4e2d\u53d1\u6325\u4f5c\u7528 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u4e3a\u786e\u4fdd\u5316\u5408\u7269\u7684\u7a33\u5b9a\u6027\u548c\u6d3b\u6027\uff0c\u5efa\u8bae\u5728-20\u00b0C\u6761\u4ef6\u4e0b\u907f\u5149\u5e72\u71e5\u50a8\u5b58\u3002\u4f7f\u7528\u65f6\u9700\u907f\u514d\u53cd\u590d\u51bb\u878d\uff0c\u5efa\u8bae\u5206\u88c5\u4fdd\u5b58\u3002\u6eb6\u89e3\u65f6\u53ef\u6839\u636e\u5b9e\u9a8c\u9700\u6c42\u9009\u62e9DMSO\u6216\u5176\u4ed6\u9002\u5f53\u6eb6\u5242\uff0c\u5e76\u786e\u4fdd\u6eb6\u6db2\u6d53\u5ea6\u7b26\u5408\u5b9e\u9a8c\u8981\u6c42\u3002\u64cd\u4f5c\u65f6\u9700\u4f69\u6234\u9632\u62a4\u88c5\u5907\uff0c\u907f\u514d\u76f4\u63a5\u63a5\u89e6\u76ae\u80a4\u6216\u5438\u5165\u7c89\u5c18\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u672c\u4ea7\u54c1\u7ecf\u8fc7\u4e25\u683c\u7684\u8d28\u91cf\u63a7\u5236\uff0c\u7eaf\u5ea6\u901a\u8fc7HPLC\u9a8c\u8bc1\uff0c\u786e\u4fdd>96%\u3002\u5b89\u5168\u4fe1\u606f\u5982\u4e0b\uff1a
\n– \u53ef\u80fd\u5bf9\u773c\u775b\u3001\u76ae\u80a4\u548c\u547c\u5438\u9053\u6709\u523a\u6fc0\u6027
\n– \u64cd\u4f5c\u65f6\u5e94\u5728\u901a\u98ce\u826f\u597d\u7684\u73af\u5883\u4e2d\u8fdb\u884c
\n– \u5982\u4e0d\u614e\u63a5\u89e6\uff0c\u5e94\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b
\n– \u5e9f\u5f03\u7269\u9700\u6309\u7167\u5b9e\u9a8c\u5ba4\u89c4\u8303\u5904\u7406\uff0c\u907f\u514d\u73af\u5883\u6c61\u67d3 <\/p>\n
\u4ee5\u4e0a\u4fe1\u606f\u4ec5\u4f9b\u53c2\u8003\uff0c\u5177\u4f53\u5b9e\u9a8c\u65b9\u6848\u9700\u6839\u636e\u5b9e\u9645\u7814\u7a76\u9700\u6c42\u8bbe\u8ba1\u3002<\/p>\n","protected":false},"featured_media":28772,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[25],"class_list":["post-54715","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-25"],"acf":[],"taxonomy_info":{"product_category":[{"value":25,"label":"\u5b9e\u9a8c\u836f\u54c1"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/2064292-52-8.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/54715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/28772"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=54715"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=54715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}