\u57c3\u535a\u9709\u7d20B (Epothilone B) \u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u57c3\u535a\u9709\u7d20B\uff08Epothilone B\uff09\u662f\u4e00\u79cd\u5927\u73af\u5185\u916f\u7c7b\u5929\u7136\u4ea7\u7269\uff0c\u5316\u5b66\u540d\u79f0\u4e3a(1S,3S,7S,10R,11S,12S,16R)-7,11-\u4e8c\u7f9f\u57fa-8,8,10,12,16-\u4e94\u7532\u57fa-3-[1-\u7532\u57fa-2-(2-\u7532\u57fa-4-\u567b\u5511\u57fa)\u4e59\u70ef\u57fa]-4,17-\u4e8c\u6c27\u6742\u53cc\u73af[14.1.0]\u5341\u4e03\u70f7-5,9-\u4e8c\u916e\uff0cCAS\u53f7\u4e3a152044-54-7\u3002\u5176\u5206\u5b50\u5f0f\u4e3aC27H41NO6S\uff0c\u5206\u5b50\u91cf\u4e3a507.682\uff0c\u7eaf\u5ea6>96%\u3002\u8be5\u5316\u5408\u7269\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7c89\u672b\uff0c\u53ef\u6eb6\u4e8eDMSO\u3001\u7532\u9187\u7b49\u6709\u673a\u6eb6\u5242\uff0c\u5fae\u6eb6\u4e8e\u6c34\uff0c\u5177\u6709\u7a33\u5b9a\u7684\u5316\u5b66\u7ed3\u6784\u548c\u660e\u786e\u7684\u7acb\u4f53\u6784\u578b\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u57c3\u535a\u9709\u7d20B\u662f\u4e00\u79cd\u5fae\u7ba1\u7a33\u5b9a\u5242\uff0c\u901a\u8fc7\u7ed3\u5408\u03b2-\u5fae\u7ba1\u86cb\u767d\u4e9a\u57fa\uff0c\u4fc3\u8fdb\u5fae\u7ba1\u805a\u5408\u5e76\u6291\u5236\u5176\u89e3\u805a\uff0c\u4ece\u800c\u963b\u65ad\u7ec6\u80de\u6709\u4e1d\u5206\u88c2\u3002\u5176\u4f5c\u7528\u673a\u5236\u4e0e\u7d2b\u6749\u9187\u7c7b\u4f3c\uff0c\u4f46\u5177\u6709\u66f4\u5f3a\u7684\u6c34\u6eb6\u6027\u548c\u5bf9\u7d2b\u6749\u9187\u8010\u836f\u7ec6\u80de\u7684\u6d3b\u6027\u3002\u57c3\u535a\u9709\u7d20B\u5728\u80bf\u7624\u7ec6\u80de\u4e2d\u53ef\u8bf1\u5bfcG2\/M\u671f\u963b\u6ede\u548c\u51cb\u4ea1\uff0c\u662f\u7814\u7a76\u5fae\u7ba1\u52a8\u529b\u5b66\u548c\u6297\u764c\u836f\u7269\u5f00\u53d1\u7684\u91cd\u8981\u5de5\u5177\u5206\u5b50\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u57c3\u535a\u9709\u7d20B\u5e7f\u6cdb\u5e94\u7528\u4e8e\u751f\u7269\u533b\u5b66\u7814\u7a76\u9886\u57df\uff0c\u5305\u62ec\uff1a
\n– \u6297\u764c\u836f\u7269\u673a\u5236\u7814\u7a76\uff1a\u4f5c\u4e3a\u5fae\u7ba1\u9776\u5411\u5242\uff0c\u7528\u4e8e\u63a2\u7d22\u80bf\u7624\u7ec6\u80de\u589e\u6b96\u6291\u5236\u9014\u5f84\u3002
\n– \u8010\u836f\u6027\u7814\u7a76\uff1a\u8bc4\u4f30\u5176\u5bf9\u591a\u836f\u8010\u836f\u80bf\u7624\u7ec6\u80de\u7cfb\u7684\u6d3b\u6027\u3002
\n– \u836f\u7269\u5f00\u53d1\uff1a\u4f5c\u4e3a\u5148\u5bfc\u5316\u5408\u7269\u7528\u4e8e\u7ed3\u6784\u4fee\u9970\u548c\u884d\u751f\u7269\u5408\u6210\u3002
\n– \u7ec6\u80de\u751f\u7269\u5b66\u7814\u7a76\uff1a\u7528\u4e8e\u5fae\u7ba1\u7f51\u7edc\u7a33\u5b9a\u6027\u7684\u4f53\u5916\u548c\u4f53\u5185\u5b9e\u9a8c\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u672c\u54c1\u9700\u907f\u5149\u4fdd\u5b58\u4e8e-20\u00b0C\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u957f\u671f\u50a8\u5b58\u5efa\u8bae\u5145\u5165\u60f0\u6027\u6c14\u4f53\u3002\u4f7f\u7528\u65f6\u9700\u5728\u65e0\u83cc\u6761\u4ef6\u4e0b\u64cd\u4f5c\uff0c\u63a8\u8350\u4ee5DMSO\u914d\u5236\u6bcd\u6db2\uff08\u598210 mM\uff09\uff0c\u5206\u88c5\u540e\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u5de5\u4f5c\u6d53\u5ea6\u9700\u6839\u636e\u5b9e\u9a8c\u4f53\u7cfb\u4f18\u5316\uff0c\u5e38\u89c4\u7ec6\u80de\u5b9e\u9a8c\u6d53\u5ea6\u8303\u56f4\u4e3a1-100 nM\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u672c\u4ea7\u54c1\u7ecfHPLC\u68c0\u6d4b\u7eaf\u5ea6>96%\uff0c\u7b26\u5408\u79d1\u7814\u7ea7\u6807\u51c6\u3002\u4f7f\u7528\u65f6\u9700\u7a7f\u6234\u9632\u62a4\u88c5\u5907\uff08\u624b\u5957\u3001\u62a4\u76ee\u955c\u7b49\uff09\uff0c\u907f\u514d\u5438\u5165\u6216\u63a5\u89e6\u76ae\u80a4\u3002\u5982\u610f\u5916\u63a5\u89e6\uff0c\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002\u5e9f\u5f03\u7269\u9700\u6309\u5371\u9669\u5316\u5b66\u54c1\u89c4\u8303\u5904\u7f6e\u3002\u672c\u54c1\u4ec5\u9650\u79d1\u7814\u7528\u9014\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u4f53\u6216\u4e34\u5e8a\u6cbb\u7597\u3002 <\/p>\n
\uff08\u5168\u6587\u5b8c\uff09<\/p>\n","protected":false},"featured_media":27080,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[25],"class_list":["post-50106","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-25"],"acf":[],"taxonomy_info":{"product_category":[{"value":25,"label":"\u5b9e\u9a8c\u836f\u54c1"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/152044-54-7.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/50106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/27080"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=50106"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=50106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}