\u4ea7\u54c1\u8bf4\u660e <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n(2R)-2-\u6c28\u57fa-3-(1H-\u5421\u54af\u5e76[2,3-b]\u5421\u5576-3-\u57fa)\u4e19\u9178\uff08\u4e2d\u6587\u540d\u79f0\uff1a(AR)-A-\u6c28\u57fa-1H-\u5421\u54af\u5e76[2,3-B]\u5421\u5576-3-\u4e19\u9178\uff09\u662f\u4e00\u79cd\u975e\u5929\u7136\u6c28\u57fa\u9178\u884d\u751f\u7269\uff0cCAS\u53f7\u4e3a134235-82-8\uff0c\u5206\u5b50\u5f0f\u4e3aC10H11N3O2\uff0c\u5206\u5b50\u91cf\u4e3a205.213\u3002\u8be5\u5316\u5408\u7269\u5177\u6709\u624b\u6027\u4e2d\u5fc3\uff0c\u5176R\u6784\u578b\u5728\u751f\u7269\u6d3b\u6027\u7814\u7a76\u4e2d\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002\u4ea7\u54c1\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u901a\u5e38\u4ee5\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7c89\u672b\u5f62\u5f0f\u5b58\u5728\uff0c\u53ef\u6eb6\u4e8e\u6c34\u53ca\u90e8\u5206\u6709\u673a\u6eb6\u5242\uff08\u5982DMSO\uff09\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u8be5\u5316\u5408\u7269\u662f\u5421\u54af\u5e76\u5421\u5576\u7c7b\u884d\u751f\u7269\uff0c\u5176\u7ed3\u6784\u4e2d\u7684\u5432\u54da\u73af\u7c7b\u4f3c\u7269\u4f7f\u5176\u5728\u751f\u7269\u4f53\u7cfb\u4e2d\u8868\u73b0\u51fa\u72ec\u7279\u7684\u6d3b\u6027\u3002\u5b83\u53ef\u4f5c\u4e3a\u6c28\u57fa\u9178\u7c7b\u4f3c\u7269\u53c2\u4e0e\u86cb\u767d\u8d28\u5408\u6210\u6216\u9176\u6291\u5236\u7814\u7a76\uff0c\u4e5f\u53ef\u80fd\u4f5c\u4e3a\u4fe1\u53f7\u5206\u5b50\u524d\u4f53\u6216\u836f\u7269\u8bbe\u8ba1\u4e2d\u7684\u5173\u952e\u4e2d\u95f4\u4f53\u3002\u7531\u4e8e\u5176\u7ed3\u6784\u4e0e\u5929\u7136\u6c28\u57fa\u9178\u76f8\u4f3c\uff0c\u5e38\u88ab\u7528\u4e8e\u7814\u7a76\u86cb\u767d\u8d28-\u914d\u4f53\u76f8\u4e92\u4f5c\u7528\u6216\u5f00\u53d1\u9776\u5411\u6cbb\u7597\u836f\u7269\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n(1) \u836f\u7269\u7814\u53d1\uff1a\u4f5c\u4e3a\u6fc0\u9176\u6291\u5236\u5242\u6216G\u86cb\u767d\u5076\u8054\u53d7\u4f53\uff08GPCR\uff09\u8c03\u8282\u5242\u7684\u6784\u5efa\u6a21\u5757\uff0c\u7528\u4e8e\u6297\u80bf\u7624\u6216\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u836f\u7269\u7684\u5f00\u53d1\u3002
\n(2) \u751f\u5316\u7814\u7a76\uff1a\u7528\u4e8e\u7814\u7a76\u6c28\u57fa\u9178\u8f6c\u8fd0\u673a\u5236\u6216\u9176\u50ac\u5316\u53cd\u5e94\u7684\u7279\u5f02\u6027\u3002
\n(3) \u80bd\u7c7b\u5408\u6210\uff1a\u4f5c\u4e3a\u975e\u5929\u7136\u6c28\u57fa\u9178\u5f15\u5165\u591a\u80bd\u94fe\u4e2d\uff0c\u4ee5\u4fee\u9970\u80bd\u7684\u7a33\u5b9a\u6027\u548c\u751f\u7269\u6d3b\u6027\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u5efa\u8bae\u5728-20\u00b0C\u4e0b\u907f\u5149\u5e72\u71e5\u50a8\u5b58\uff0c\u957f\u671f\u4fdd\u5b58\u9700\u7f6e\u4e8e\u60f0\u6027\u6c14\u4f53\u73af\u5883\u4e2d\u3002\u4f7f\u7528\u65f6\u9700\u5728\u5e72\u71e5\u73af\u5883\u4e0b\u64cd\u4f5c\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u6eb6\u89e3\u524d\u5efa\u8bae\u8fdb\u884c\u77ed\u6682\u8d85\u58f0\u5904\u7406\u4ee5\u63d0\u9ad8\u6eb6\u89e3\u5ea6\u3002\u5b9e\u9a8c\u8fc7\u7a0b\u4e2d\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u548c\u62a4\u76ee\u955c\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u672c\u4ea7\u54c1\u901a\u8fc7HPLC\u9a8c\u8bc1\u7eaf\u5ea6\uff0c\u5e76\u63d0\u4f9b\u8d28\u8c31\u548c\u6838\u78c1\u6570\u636e\u4ee5\u786e\u4fdd\u7ed3\u6784\u51c6\u786e\u6027\u3002\u5b89\u5168\u4fe1\u606f\u663e\u793a\uff0c\u8be5\u5316\u5408\u7269\u53ef\u80fd\u5bf9\u773c\u775b\u548c\u76ae\u80a4\u6709\u523a\u6fc0\u6027\uff0c\u64cd\u4f5c\u65f6\u5e94\u9075\u5b88\u5b9e\u9a8c\u5ba4\u5b89\u5168\u89c4\u8303\u3002\u5982\u63a5\u89e6\u76ae\u80a4\uff0c\u9700\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u3002\u5e9f\u5f03\u7269\u5e94\u6309\u7167\u5371\u9669\u5316\u5b66\u54c1\u5904\u7406\u6807\u51c6\u5904\u7f6e\u3002 <\/p>\n
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