1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u4e1d\u88c2\u9709\u7d20\uff08Mitomycin C\uff09\u662f\u4e00\u79cd\u5177\u6709\u6297\u80bf\u7624\u6d3b\u6027\u7684\u6297\u751f\u7d20\u7c7b\u5316\u5408\u7269\uff0c\u5316\u5b66\u540d\u79f0\u4e3a5-\u6c28\u57fa-3-[(1S,6S,7R,8S)-8-\u7532\u6c27\u57fa-5-\u7532\u57fa-4,7-\u4e8c\u6c27\u4ee3-2-\u6c27\u6742-6-\u6c2e\u6742\u53cc\u73af[3.2.1]\u8f9b-3-\u57fa]\u6c28\u57fa-6-\u7532\u57fa-1H,5H-\u82ef\u5e76[ij]\u55b9\u55ea-2,7-\u4e8c\u916e\u3002\u5176CAS\u53f7\u4e3a50-07-7\uff0c\u5206\u5b50\u5f0f\u4e3aC15H18N4O5\uff0c\u5206\u5b50\u91cf\u4e3a334.327\u3002\u672c\u54c1\u4e3a\u6df1\u7d2b\u8272\u7ed3\u6676\u6216\u7c89\u672b\uff0c\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u53ef\u6eb6\u4e8e\u6c34\u3001\u7532\u9187\u548c\u4e59\u9187\uff0c\u4f46\u5728\u5149\u7167\u4e0b\u6613\u5206\u89e3\uff0c\u9700\u907f\u5149\u4fdd\u5b58\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4e1d\u88c2\u9709\u7d20\u901a\u8fc7\u70f7\u5316DNA\u53cc\u94fe\uff0c\u5f62\u6210\u4ea4\u8054\u7ed3\u6784\uff0c\u4ece\u800c\u6291\u5236DNA\u590d\u5236\u548c\u8f6c\u5f55\uff0c\u6700\u7ec8\u5bfc\u81f4\u7ec6\u80de\u51cb\u4ea1\u3002\u5176\u4f5c\u7528\u673a\u5236\u4f9d\u8d56\u4e8e\u8fd8\u539f\u6d3b\u5316\u8fc7\u7a0b\uff0c\u5728\u4f4e\u6c27\u73af\u5883\u4e0b\uff08\u5982\u5b9e\u4f53\u7624\u5fae\u73af\u5883\uff09\u6d3b\u6027\u663e\u8457\u589e\u5f3a\u3002\u8fd9\u4e00\u7279\u6027\u4f7f\u5176\u6210\u4e3a\u7814\u7a76DNA\u635f\u4f24\u4fee\u590d\u673a\u5236\u7684\u91cd\u8981\u5de5\u5177\uff0c\u4e5f\u662f\u6297\u80bf\u7624\u836f\u7269\u5f00\u53d1\u7684\u7ecf\u5178\u6a21\u578b\u5316\u5408\u7269\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u5728\u79d1\u7814\u9886\u57df\uff0c\u4e1d\u88c2\u9709\u7d20\u5e38\u7528\u4e8e\u8bf1\u5bfc\u7ec6\u80de\u5468\u671f\u963b\u6ede\u3001\u6784\u5efaDNA\u635f\u4f24\u6a21\u578b\u53ca\u7b5b\u9009DNA\u4fee\u590d\u6291\u5236\u5242\u3002\u4e34\u5e8a\u4e0a\uff0c\u5b83\u88ab\u7528\u4e8e\u6cbb\u7597\u80c3\u764c\u3001\u8180\u80f1\u764c\u7b49\u5b9e\u4f53\u7624\uff0c\u5e38\u4f5c\u4e3a\u5316\u7597\u65b9\u6848\u7684\u7ec4\u6210\u90e8\u5206\u3002\u6b64\u5916\uff0c\u5728\u773c\u79d1\u624b\u672f\u4e2d\u7528\u4e8e\u6291\u5236\u89d2\u819c\u4e0a\u76ae\u7ec6\u80de\u589e\u6b96\uff0c\u9632\u6b62\u672f\u540e\u7622\u75d5\u5f62\u6210\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u672c\u54c1\u9700\u4e25\u683c\u907f\u5149\uff0c\u5bc6\u5c01\u4fdd\u5b58\u4e8e-20\u2103\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u957f\u671f\u50a8\u5b58\u5efa\u8bae\u5145\u6c2e\u4fdd\u62a4\u3002\u4f7f\u7528\u65f6\u9700\u5728\u51b0\u4e0a\u6eb6\u89e3\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u5de5\u4f5c\u6db2\u5e94\u73b0\u914d\u73b0\u7528\uff0c\u5269\u4f59\u6eb6\u6db2\u9700\u4e22\u5f03\u3002\u64cd\u4f5c\u65f6\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u3001\u62a4\u76ee\u955c\u53ca\u5b9e\u9a8c\u670d\uff0c\u786e\u4fdd\u901a\u98ce\u826f\u597d\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u901a\u8fc7HPLC\u68c0\u6d4b\u786e\u8ba4\u7eaf\u5ea6\uff1e96%\uff0c\u6b8b\u7559\u6eb6\u5242\u7b26\u5408USP\u6807\u51c6\u3002\u672c\u54c1\u4e3a\u5267\u6bd2\u7269\u8d28\uff08LD50\u5c0f\u9f20\u9759\u8109\u6ce8\u5c04\u7ea65mg\/kg\uff09\uff0c\u53ef\u80fd\u5f15\u8d77\u9aa8\u9ad3\u6291\u5236\u3001\u80ba\u7ea4\u7ef4\u5316\u7b49\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u3002\u5e9f\u5f03\u7269\u9700\u6309\u5371\u9669\u5316\u5b66\u54c1\u89c4\u8303\u5904\u7f6e\uff0c\u7d27\u6025\u63a5\u89e6\u65f6\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002 <\/p>\n
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