5′-O-\u4e09\u82ef\u7532\u57fa\u80f8\u82f7\u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n5′-O-\u4e09\u82ef\u7532\u57fa\u80f8\u82f7\uff085′-O-Tritylthymidine\uff0cCAS\u53f77791-71-1\uff09\u662f\u4e00\u79cd\u91cd\u8981\u7684\u80f8\u82f7\u884d\u751f\u7269\uff0c\u5206\u5b50\u5f0f\u4e3aC29H28N2O5\uff0c\u5206\u5b50\u91cf484.543\u3002\u8be5\u5316\u5408\u7269\u901a\u8fc7\u80f8\u82f75′-\u7f9f\u57fa\u4e0e\u4e09\u82ef\u7532\u57fa\uff08Trityl\uff09\u57fa\u56e2\u7279\u5f02\u6027\u7ed3\u5408\u5f62\u6210\uff0c\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u5916\u89c2\u901a\u5e38\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7c89\u672b\u3002\u5176\u7ed3\u6784\u4e2d\u7684\u4e09\u82ef\u7532\u57fa\u4fdd\u62a4\u57fa\u8d4b\u4e88\u5206\u5b50\u72ec\u7279\u7684\u7a7a\u95f4\u4f4d\u963b\u6548\u5e94\uff0c\u4f7f\u5176\u5728\u6838\u82f7\u9178\u5316\u5b66\u5408\u6210\u4e2d\u8868\u73b0\u51fa\u9ad8\u53cd\u5e94\u9009\u62e9\u6027\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u80f8\u82f7\u7684\u4fee\u9970\u5f62\u5f0f\uff0c5′-O-\u4e09\u82ef\u7532\u57fa\u80f8\u82f7\u5728\u6838\u9178\u5316\u5b66\u4e2d\u626e\u6f14\u5173\u952e\u89d2\u8272\u3002\u51765′-OH\u7684\u4fdd\u62a4\u53ef\u6709\u6548\u907f\u514d\u6838\u82f7\u9178\u94fe\u5ef6\u4f38\u8fc7\u7a0b\u4e2d\u7684\u526f\u53cd\u5e94\uff0c\u786e\u4fdd\u5be1\u6838\u82f7\u9178\u5408\u6210\u7684\u5b9a\u5411\u6027\u4e0e\u51c6\u786e\u6027\u3002\u8be5\u7279\u6027\u4f7f\u5176\u6210\u4e3a\u56fa\u76f8\u5408\u6210\u6cd5\u6784\u5efaDNA\/RNA\u5e8f\u5217\u7684\u91cd\u8981\u4e2d\u95f4\u4f53\uff0c\u5c24\u5176\u5728\u81ea\u52a8\u5316\u5408\u6210\u4eea\u4e2d\u5e7f\u6cdb\u5e94\u7528\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u672c\u4ea7\u54c1\u4e3b\u8981\u7528\u4e8e\u4ee5\u4e0b\u9886\u57df\uff1a
\n3.1 \u6838\u9178\u836f\u7269\u5f00\u53d1\uff1a\u4f5c\u4e3a\u5408\u6210\u6297\u75c5\u6bd2\u836f\u7269\uff08\u5982AZT\u7c7b\u4f3c\u7269\uff09\u6216\u53cd\u4e49\u5be1\u6838\u82f7\u9178\u7684\u5173\u952e\u539f\u6599\u3002
\n3.2 \u5206\u5b50\u751f\u7269\u5b66\u7814\u7a76\uff1a\u7528\u4e8e\u5236\u5907\u8367\u5149\u6807\u8bb0\u63a2\u9488\u6216\u4fee\u9970\u6838\u82f7\u9178\uff0c\u652f\u6301\u57fa\u56e0\u68c0\u6d4b\u4e0e\u6d4b\u5e8f\u6280\u672f\u3002
\n3.3 \u5316\u5b66\u5408\u6210\uff1a\u4f5c\u4e3a\u4fdd\u62a4\u57fa\u4e2d\u95f4\u4f53\u53c2\u4e0e\u590d\u6742\u6838\u82f7\u884d\u751f\u7269\u7684\u9010\u6b65\u6784\u5efa\uff0c\u4f8b\u5982\u7cd6\u57fa\u5316\u4fee\u9970\u6216\u78f7\u9178\u5316\u53cd\u5e94\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n4.1 \u50a8\u5b58\u6761\u4ef6\uff1a\u5efa\u8bae\u5bc6\u5c01\u4fdd\u5b58\u4e8e-20\u2103\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u907f\u514d\u5149\u7167\u4e0e\u6e7f\u6c14\u3002\u957f\u671f\u50a8\u5b58\u9700\u5145\u60f0\u6027\u6c14\u4f53\uff08\u5982\u6c2e\u6c14\uff09\u4fdd\u62a4\u3002
\n4.2 \u4f7f\u7528\u5efa\u8bae\uff1a\u4f7f\u7528\u524d\u9700\u6062\u590d\u81f3\u5ba4\u6e29\u5e76\u5e72\u71e5\u5904\u7406\u3002\u6eb6\u4e8e\u65e0\u6c34DMF\u6216\u4e59\u8148\u65f6\u6d3b\u6027\u6700\u4f73\uff0c\u53cd\u5e94\u4f53\u7cfb\u5e94\u4e25\u683c\u9664\u6c34\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n5.1 \u8d28\u91cf\u63a7\u5236\uff1a\u901a\u8fc7HPLC\u9a8c\u8bc1\u7eaf\u5ea6\uff08>96%\uff09\uff0c\u8d28\u8c31\u4e0e\u6838\u78c1\u5171\u632f\u8c31\uff081H-NMR\uff09\u786e\u8ba4\u7ed3\u6784\u4e00\u81f4\u6027\u3002
\n5.2 \u5b89\u5168\u4fe1\u606f\uff1a\u672c\u54c1\u5bf9\u773c\u775b\u548c\u547c\u5438\u9053\u6709\u8f7b\u5fae\u523a\u6fc0\u6027\uff0c\u64cd\u4f5c\u65f6\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u4e0e\u62a4\u76ee\u955c\u3002\u82e5\u4e0d\u614e\u63a5\u89e6\uff0c\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002\u5e9f\u5f03\u7269\u5e94\u4f5c\u4e3a\u6709\u5bb3\u5316\u5b66\u7269\u8d28\u5904\u7406\uff0c\u9075\u5b88\u5f53\u5730\u73af\u4fdd\u6cd5\u89c4\u3002 <\/p>\n
\u672c\u4ea7\u54c1\u4ec5\u4f9b\u79d1\u7814\u7528\u9014\uff0c\u4e0d\u9002\u7528\u4e8e\u4e34\u5e8a\u6216\u98df\u54c1\u9886\u57df\u3002\u5177\u4f53\u4f7f\u7528\u65b9\u6848\u5efa\u8bae\u53c2\u8003\u76f8\u5173\u6587\u732e\u6216\u54a8\u8be2\u4e13\u4e1a\u6280\u672f\u652f\u6301\u3002<\/p>\n","protected":false},"featured_media":35640,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[25],"class_list":["post-49718","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-25"],"acf":[],"taxonomy_info":{"product_category":[{"value":25,"label":"\u5b9e\u9a8c\u836f\u54c1"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/7791-71-1.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/49718","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/35640"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=49718"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=49718"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}