3-\u6c1f-4-\u7532\u6c27\u57fa\u6eb4\u82c4\u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u672c\u4ea7\u54c1\u5316\u5b66\u540d\u79f0\u4e3a4-(\u6eb4\u7532\u57fa)-2-\u6c1f-1-\u7532\u6c27\u57fa\u82ef\uff084-(bromomethyl)-2-fluoro-1-methoxybenzene\uff09\uff0cCAS\u53f7\u4e3a331-61-3\uff0c\u5206\u5b50\u5f0f\u4e3aC8H8BrFO\uff0c\u5206\u5b50\u91cf219.051\u3002\u5176\u4e3a\u65e0\u8272\u81f3\u6de1\u9ec4\u8272\u6db2\u4f53\u6216\u4f4e\u7194\u70b9\u56fa\u4f53\uff0c\u7eaf\u5ea6\u9ad8\u4e8e96%\uff0c\u5177\u6709\u82b3\u70c3\u7279\u5f81\u6c14\u5473\u3002\u8be5\u5316\u5408\u7269\u542b\u6c1f\u3001\u6eb4\u4e24\u79cd\u5364\u7d20\u5b98\u80fd\u56e2\u53ca\u7532\u6c27\u57fa\uff0c\u517c\u5177\u4eb2\u7535\u6027\u4e0e\u7a7a\u95f4\u4f4d\u963b\u6548\u5e94\uff0c\u662f\u91cd\u8981\u7684\u6709\u673a\u5408\u6210\u4e2d\u95f4\u4f53\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u82ef\u73af\u4fee\u9970\u5316\u5408\u7269\uff0c\u5176\u6eb4\u7532\u57fa\u53ef\u53c2\u4e0e\u4eb2\u6838\u53d6\u4ee3\u53cd\u5e94\uff0c\u6c1f\u539f\u5b50\u589e\u5f3a\u7535\u5b50\u4eb2\u548c\u6027\uff0c\u7532\u6c27\u57fa\u5219\u63d0\u4f9b\u4f9b\u7535\u5b50\u6548\u5e94\u3002\u8fd9\u79cd\u591a\u5b98\u80fd\u56e2\u7ed3\u6784\u4f7f\u5176\u5728\u6784\u5efa\u590d\u6742\u5206\u5b50\u9aa8\u67b6\u65f6\u5177\u6709\u72ec\u7279\u4f18\u52bf\uff0c\u5c24\u5176\u5728\u836f\u7269\u5316\u5b66\u4e2d\u5e38\u7528\u4e8e\u5f15\u5165\u6c1f\u4ee3\u82ef\u7532\u57fa\u7247\u6bb5\uff0c\u4ee5\u8c03\u8282\u5316\u5408\u7269\u7684\u8102\u6eb6\u6027\u3001\u4ee3\u8c22\u7a33\u5b9a\u6027\u548c\u751f\u7269\u6d3b\u6027\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n\u8be5\u4ea7\u54c1\u4e3b\u8981\u7528\u4e8e\u533b\u836f\u548c\u6750\u6599\u79d1\u5b66\u9886\u57df\u3002\u5728\u533b\u836f\u7814\u53d1\u4e2d\uff0c\u53ef\u4f5c\u4e3a\u6297\u80bf\u7624\u3001\u6297\u83cc\u836f\u7269\u7684\u5173\u952e\u4e2d\u95f4\u4f53\uff0c\u4f8b\u5982\u7528\u4e8e\u5408\u6210\u6c1f\u4ee3\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\u3002\u5728\u6750\u6599\u9886\u57df\uff0c\u53ef\u7528\u4e8e\u5236\u5907\u542b\u6c1f\u6db2\u6676\u5355\u4f53\u6216\u9ad8\u5206\u5b50\u6539\u6027\u5242\u3002\u6b64\u5916\uff0c\u5728\u519c\u836f\u5316\u5b66\u4e2d\u4e5f\u6709\u5e94\u7528\uff0c\u5982\u5408\u6210\u9ad8\u6548\u4f4e\u6bd2\u6740\u866b\u5242\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u9700\u907f\u5149\u5bc6\u5c01\u4fdd\u5b58\u4e8e2-8\u2103\u60f0\u6027\u6c14\u4f53\u73af\u5883\u4e2d\uff0c\u77ed\u671f\u4f7f\u7528\u53ef\u7f6e\u4e8e\u5e72\u71e5\u5668\u5185\u3002\u5f00\u5c01\u540e\u5efa\u8bae\u5145\u6c2e\u4fdd\u62a4\u5e76\u5c3d\u5feb\u4f7f\u7528\u3002\u64cd\u4f5c\u65f6\u9700\u5728\u901a\u98ce\u6a71\u4e2d\u8fdb\u884c\uff0c\u4f69\u6234\u9632\u5316\u624b\u5957\u4e0e\u62a4\u76ee\u955c\u3002\u907f\u514d\u4e0e\u5f3a\u6c27\u5316\u5242\u3001\u5f3a\u9178\u5f3a\u78b1\u63a5\u89e6\uff0c\u8fd0\u8f93\u4e2d\u9700\u7b26\u5408\u5371\u9669\u5316\u5b66\u54c1\u89c4\u8303\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n\u672c\u4ea7\u54c1\u7ecfHPLC\u68c0\u6d4b\u7eaf\u5ea6\u226596%\uff0c\u6c34\u5206\u542b\u91cf\u22640.5%\uff0c\u6b8b\u7559\u6eb6\u5242\u7b26\u5408ICH\u6807\u51c6\u3002\u5b89\u5168\u6570\u636e\u8868\u660e\uff0c\u5176\u5bf9\u76ae\u80a4\u3001\u773c\u775b\u6709\u523a\u6fc0\u6027\uff0c\u53ef\u80fd\u5f15\u8d77\u547c\u5438\u9053\u8fc7\u654f\u3002\u5e94\u6025\u5904\u7406\u65f6\u9700\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u63a5\u89e6\u90e8\u4f4d\uff0c\u5438\u5165\u540e\u7acb\u5373\u8f6c\u79fb\u81f3\u7a7a\u6c14\u65b0\u9c9c\u5904\u3002\u5e9f\u5f03\u7269\u5904\u7f6e\u5e94\u9075\u7167\u5f53\u5730\u73af\u4fdd\u6cd5\u89c4\uff0c\u4e0d\u53ef\u76f4\u63a5\u6392\u5165\u4e0b\u6c34\u7cfb\u7edf\u3002 <\/p>\n
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