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N-Demethylofloxacin\uff08\u6c27\u6c1f\u6c99\u661f\u76f8\u5173\u7269\u8d28A\uff09\u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n

1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
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2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u6c27\u6c1f\u6c99\u661f\u7684\u53bb\u7532\u57fa\u5316\u4ee3\u8c22\u7269\uff0cN-Demethylofloxacin\u4fdd\u7559\u4e86\u55b9\u8bfa\u916e\u7c7b\u836f\u7269\u7684\u6838\u5fc3\u7ed3\u6784\uff0c\u80fd\u591f\u4e0e\u7ec6\u83ccDNA\u65cb\u8f6c\u9176\u548c\u62d3\u6251\u5f02\u6784\u9176IV\u7ed3\u5408\uff0c\u6291\u5236\u7ec6\u83ccDNA\u590d\u5236\u3002\u5176\u751f\u7269\u6d3b\u6027\u7814\u7a76\u6709\u52a9\u4e8e\u7406\u89e3\u6c27\u6c1f\u6c99\u661f\u7684\u4ee3\u8c22\u9014\u5f84\u548c\u836f\u6548\u5b66\u7279\u6027\u3002\u6b64\u5916\uff0c\u8be5\u7269\u8d28\u5728\u836f\u7269\u6b8b\u7559\u5206\u6790\u548c\u4ee3\u8c22\u52a8\u529b\u5b66\u7814\u7a76\u4e2d\u4f5c\u4e3a\u5173\u952e\u5bf9\u7167\u54c1\uff0c\u4e3a\u6297\u751f\u7d20\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u8bc4\u4f30\u63d0\u4f9b\u79d1\u5b66\u4f9d\u636e\u3002 <\/p>\n

3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\nN-Demethylofloxacin\u4e3b\u8981\u7528\u4e8e\u4ee5\u4e0b\u9886\u57df\uff1a\u5236\u836f\u5de5\u4e1a\u4e2d\u4f5c\u4e3a\u6c27\u6c1f\u6c99\u661f\u751f\u4ea7\u5de5\u827a\u7684\u6742\u8d28\u5bf9\u7167\u54c1\uff1b\u4e34\u5e8a\u7814\u7a76\u4e2d\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\u7684\u6807\u8bb0\u7269\uff1b\u98df\u54c1\u5b89\u5168\u68c0\u6d4b\u4e2d\u7528\u4e8e\u52a8\u7269\u6e90\u6027\u98df\u54c1\u7684\u6297\u751f\u7d20\u6b8b\u7559\u5206\u6790\u3002\u5728\u79d1\u7814\u9886\u57df\uff0c\u8be5\u5316\u5408\u7269\u53ef\u7528\u4e8e\u7ec6\u83cc\u8010\u836f\u6027\u673a\u5236\u7814\u7a76\u53ca\u65b0\u578b\u55b9\u8bfa\u916e\u7c7b\u836f\u7269\u7684\u5f00\u53d1\u3002 <\/p>\n

4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n\u672c\u4ea7\u54c1\u9700\u907f\u5149\u4fdd\u5b58\u4e8e2-8\u2103\u7684\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u957f\u671f\u50a8\u5b58\u5efa\u8bae\u7f6e\u4e8e-20\u2103\u3002\u5f00\u5c01\u540e\u9700\u5145\u5165\u60f0\u6027\u6c14\u4f53\uff08\u5982\u6c2e\u6c14\uff09\u5bc6\u5c01\uff0c\u9632\u6b62\u5438\u6e7f\u548c\u6c27\u5316\u3002\u4f7f\u7528\u65f6\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u548c\u62a4\u76ee\u955c\uff0c\u907f\u514d\u76f4\u63a5\u63a5\u89e6\u76ae\u80a4\u6216\u5438\u5165\u7c89\u5c18\u3002\u6eb6\u89e3\u5efa\u8bae\u4f7f\u7528DMSO\u6216\u78b1\u6027\u6c34\u6eb6\u6db2\uff08pH>9\uff09\uff0c\u914d\u5236\u540e\u6eb6\u6db2\u9700\u73b0\u914d\u73b0\u7528\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002 <\/p>\n

5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
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