L-N-BOC-5-\u6c1f\u8272\u6c28\u9178\u4ea7\u54c1\u8bf4\u660e\u4e66 <\/p>\n
1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027
\n\u672c\u54c1\u5316\u5b66\u540d\u79f0\u4e3a(2S)-3-(5-fluoro-1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid\uff0c\u662f\u4e00\u79cd\u91cd\u8981\u7684\u8272\u6c28\u9178\u884d\u751f\u7269\u3002\u5176\u5206\u5b50\u5f0f\u4e3aC16H19FN2O4\uff0c\u5206\u5b50\u91cf322.332\uff0cCAS\u53f7\u4e3a53478-53-8\u3002\u4ea7\u54c1\u4e3a\u767d\u8272\u81f3\u7c7b\u767d\u8272\u7ed3\u6676\u6027\u7c89\u672b\uff0c\u7eaf\u5ea6\u7ecfHPLC\u68c0\u6d4b\u5927\u4e8e96%\u3002\u7ed3\u6784\u4e2d\u7684BOC\uff08\u53d4\u4e01\u6c27\u7fb0\u57fa\uff09\u4fdd\u62a4\u57fa\u56e2\u548c5-\u4f4d\u6c1f\u539f\u5b50\u4fee\u9970\u8d4b\u4e88\u5176\u72ec\u7279\u7684\u5316\u5b66\u7a33\u5b9a\u6027\u53ca\u751f\u7269\u6d3b\u6027\u3002 <\/p>\n
2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027
\n\u4f5c\u4e3a\u6c1f\u4ee3\u8272\u6c28\u9178\u7684BOC\u4fdd\u62a4\u5f62\u5f0f\uff0c\u672c\u54c1\u662f\u5408\u6210\u591a\u80bd\u7c7b\u5316\u5408\u7269\u7684\u5173\u952e\u4e2d\u95f4\u4f53\uff0c\u7279\u522b\u9002\u7528\u4e8e\u56fa\u76f8\u80bd\u5408\u6210\uff08SPPS\uff09\u3002\u6c1f\u539f\u5b50\u7684\u5f15\u5165\u53ef\u589e\u5f3a\u6bcd\u4f53\u5206\u5b50\u7684\u758f\u6c34\u6027\u548c\u4ee3\u8c22\u7a33\u5b9a\u6027\uff0c\u800cBOC\u4fdd\u62a4\u57fa\u80fd\u6709\u6548\u9632\u6b62\u6c28\u57fa\u5728\u53cd\u5e94\u4e2d\u7684\u526f\u53cd\u5e94\u3002\u5176\u5728\u86cb\u767d\u8d28\u7ed3\u6784\u7814\u7a76\u3001\u9176\u6291\u5236\u5242\u5f00\u53d1\u53ca\u653e\u5c04\u6027\u6807\u8bb0\u7b49\u9886\u57df\u5177\u6709\u4e0d\u53ef\u66ff\u4ee3\u7684\u4f5c\u7528\u3002 <\/p>\n
3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014
\n3.1 \u533b\u836f\u7814\u53d1\uff1a\u7528\u4e8e\u542b\u6c1f\u80bd\u7c7b\u836f\u7269\u7684\u5408\u6210\uff0c\u5982\u6297\u80bf\u7624\u548c\u6297\u75c5\u6bd2\u5019\u9009\u836f\u7269\u3002
\n3.2 \u751f\u5316\u7814\u7a76\uff1a\u4f5c\u4e3a\u8367\u5149\u63a2\u9488\u6216\u6838\u78c1\u5171\u632f\uff08NMR\uff09\u6807\u8bb0\u7269\uff0c\u7814\u7a76\u86cb\u767d\u8d28\u6298\u53e0\u4e0e\u76f8\u4e92\u4f5c\u7528\u3002
\n3.3 \u653e\u5c04\u6027\u793a\u8e2a\uff1a\u901a\u8fc718F\u6807\u8bb0\u5236\u5907\u6b63\u7535\u5b50\u53d1\u5c04\u65ad\u5c42\u626b\u63cf\uff08PET\uff09\u663e\u5f71\u5242\u3002 <\/p>\n
4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae
\n4.1 \u50a8\u5b58\uff1a\u5bc6\u5c01\u907f\u5149\u4fdd\u5b58\u4e8e-20\u00b0C\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u957f\u671f\u50a8\u5b58\u5efa\u8bae\u5145\u6c2e\u4fdd\u62a4\u3002
\n4.2 \u6eb6\u89e3\u6027\uff1a\u6613\u6eb6\u4e8e\u4e8c\u7532\u57fa\u4e9a\u781c\uff08DMSO\uff09\u3001\u4e8c\u6c2f\u7532\u70f7\uff0c\u5fae\u6eb6\u4e8e\u7532\u9187\u3002
\n4.3 \u4f7f\u7528\uff1a\u5efa\u8bae\u5728\u60f0\u6027\u6c14\u4f53\u73af\u5883\u4e0b\u64cd\u4f5c\uff0c\u907f\u514d\u53cd\u590d\u51bb\u878d\uff1b\u53bb\u9664BOC\u4fdd\u62a4\u57fa\u65f6\u9700\u4f7f\u7528\u4e09\u6c1f\u4e59\u9178\uff08TFA\uff09\u7b49\u9178\u6027\u6761\u4ef6\u3002 <\/p>\n
5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f
\n5.1 \u8d28\u91cf\u63a7\u5236\uff1a\u901a\u8fc7HPLC\u3001\u8d28\u8c31\uff08MS\uff09\u53ca\u6838\u78c1\u5171\u632f\u6c22\u8c31\uff081H NMR\uff09\u8fdb\u884c\u6279\u6b21\u9a8c\u8bc1\u3002
\n5.2 \u5b89\u5168\u8b66\u793a\uff1a\u672c\u54c1\u5bf9\u773c\u775b\u548c\u547c\u5438\u9053\u6709\u8f7b\u5fae\u523a\u6fc0\u6027\uff0c\u64cd\u4f5c\u65f6\u9700\u4f69\u6234\u9632\u62a4\u624b\u5957\u53ca\u62a4\u76ee\u955c\u3002
\n5.3 \u5e9f\u5f03\u7269\u5904\u7406\uff1a\u6309\u5371\u9669\u5316\u5b66\u54c1\u89c4\u8303\u5904\u7f6e\uff0c\u907f\u514d\u76f4\u63a5\u63a5\u89e6\u5f3a\u6c27\u5316\u5242\u3002 <\/p>\n
\u672c\u4ea7\u54c1\u4ec5\u4f9b\u79d1\u7814\u7528\u9014\uff0c\u4e0d\u9002\u7528\u4e8e\u4e34\u5e8a\u6216\u98df\u54c1\u9886\u57df\u3002\u5177\u4f53\u4f7f\u7528\u65b9\u6848\u9700\u7ed3\u5408\u5b9e\u9a8c\u76ee\u7684\u8fdb\u4e00\u6b65\u4f18\u5316\u3002<\/p>\n","protected":false},"featured_media":32883,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[25],"class_list":["post-47212","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-25"],"acf":[],"taxonomy_info":{"product_category":[{"value":25,"label":"\u5b9e\u9a8c\u836f\u54c1"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/53478-53-8.jpg",464,464,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/47212","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/32883"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=47212"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=47212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}