{"id":128930,"date":"2026-05-07T22:15:18","date_gmt":"2026-05-07T14:15:18","guid":{"rendered":"http:\/\/111.62.156.167\/?chemical-product=%e7%9a%84mtor-in-1"},"modified":"2026-05-07T22:15:18","modified_gmt":"2026-05-07T14:15:18","slug":"%e7%9a%84mtor-in-1","status":"publish","type":"chemical-product","link":"https:\/\/bio-get.com\/?chemical-product=%e7%9a%84mtor-in-1","title":{"rendered":"\u7684mTOR-IN-1"},"content":{"rendered":"<p>\u4ea7\u54c1\u8bf4\u660e<br \/>\n1. \u4ea7\u54c1\u6982\u8ff0\u4e0e\u5316\u5b66\u7279\u6027<br \/>\nmTOR-IN-1\uff08\u5316\u5b66\u540d\u79f0\uff1a1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea\uff09\u662f\u4e00\u79cd\u5c0f\u5206\u5b50\u6291\u5236\u5242\uff0cCAS\u53f7\u4e3a1207358-59-5\uff0c\u5206\u5b50\u5f0f\u4e3aC25H30N8O2\uff0c\u5206\u5b50\u91cf\u4e3a474.558\u3002\u8be5\u5316\u5408\u7269\u5177\u6709\u9ad8\u7eaf\u5ea6\uff08\u226796%\uff09\uff0c\u7ed3\u6784\u4e2d\u542b\u6709\u5421\u5576\u5e76\u5627\u5576\u6838\u5fc3\u548c\u5417\u5549\u73af\uff0c\u662f\u4e00\u79cd\u7279\u5f02\u6027\u9776\u5411mTOR\uff08\u54fa\u4e73\u52a8\u7269\u96f7\u5e15\u9709\u7d20\u9776\u86cb\u767d\uff09\u7684\u6291\u5236\u5242\u3002\u5176\u5316\u5b66\u6027\u8d28\u7a33\u5b9a\uff0c\u9002\u5408\u7528\u4e8e\u751f\u7269\u5316\u5b66\u548c\u836f\u7406\u5b66\u7814\u7a76\u3002<br \/>\n2. \u751f\u7269\u5316\u5b66\u529f\u80fd\u4e0e\u91cd\u8981\u6027<br \/>\nmTOR-IN-1\u901a\u8fc7\u9009\u62e9\u6027\u6291\u5236mTOR\u4fe1\u53f7\u901a\u8def\uff0c\u5e72\u6270\u7ec6\u80de\u589e\u6b96\u3001\u4ee3\u8c22\u548c\u81ea\u566c\u7b49\u5173\u952e\u751f\u7269\u5b66\u8fc7\u7a0b\u3002mTOR\u662fPI3K\/AKT\/mTOR\u901a\u8def\u7684\u6838\u5fc3\u7ec4\u5206\uff0c\u5728\u80bf\u7624\u53d1\u751f\u3001\u514d\u75ab\u8c03\u8282\u548c\u4ee3\u8c22\u75be\u75c5\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002\u8be5\u5316\u5408\u7269\u80fd\u591f\u6709\u6548\u6291\u5236mTORC1\u548cmTORC2\u7684\u6d3b\u6027\uff0c\u4e3a\u7814\u7a76mTOR\u76f8\u5173\u75be\u75c5\u673a\u5236\u53ca\u836f\u7269\u5f00\u53d1\u63d0\u4f9b\u4e86\u91cd\u8981\u5de5\u5177\u3002<br \/>\n3. \u4e3b\u8981\u5e94\u7528\u9886\u57df\u4e0e\u5177\u4f53\u7528\u9014<br \/>\nmTOR-IN-1\u5e7f\u6cdb\u5e94\u7528\u4e8e\u764c\u75c7\u7814\u7a76\u3001\u514d\u75ab\u5b66\u7814\u7a76\u548c\u4ee3\u8c22\u75be\u75c5\u7814\u7a76\u9886\u57df\u3002\u5177\u4f53\u7528\u9014\u5305\u62ec\uff1a<br \/>\n&#8211; \u4f5c\u4e3amTOR\u901a\u8def\u7814\u7a76\u7684\u5de5\u5177\u5316\u5408\u7269\uff0c\u7528\u4e8e\u4f53\u5916\u548c\u4f53\u5185\u5b9e\u9a8c\u3002<br \/>\n&#8211; \u7528\u4e8e\u7b5b\u9009\u548c\u5f00\u53d1\u65b0\u578b\u6297\u80bf\u7624\u836f\u7269\uff0c\u8bc4\u4f30mTOR\u6291\u5236\u5242\u7684\u7597\u6548\u3002<br \/>\n&#8211; \u7814\u7a76mTOR\u5728\u7ec6\u80de\u81ea\u566c\u3001\u4ee3\u8c22\u91cd\u7f16\u7a0b\u548c\u514d\u75ab\u8c03\u8282\u4e2d\u7684\u4f5c\u7528\u673a\u5236\u3002<br \/>\n4. \u50a8\u5b58\u6761\u4ef6\u4e0e\u4f7f\u7528\u5efa\u8bae<br \/>\n\u672c\u54c1\u5e94\u907f\u5149\u4fdd\u5b58\u4e8e-20\u00b0C\u5e72\u71e5\u73af\u5883\u4e2d\uff0c\u957f\u671f\u50a8\u5b58\u5efa\u8bae\u7f6e\u4e8e\u60f0\u6027\u6c14\u4f53\u4fdd\u62a4\u4e0b\u3002\u4f7f\u7528\u65f6\u9700\u6eb6\u89e3\u4e8eDMSO\u6216\u5176\u4ed6\u9002\u5f53\u6eb6\u5242\uff0c\u914d\u5236\u6210\u5de5\u4f5c\u6db2\u540e\u907f\u514d\u53cd\u590d\u51bb\u878d\u3002\u5b9e\u9a8c\u64cd\u4f5c\u9700\u5728\u751f\u7269\u5b89\u5168\u67dc\u4e2d\u8fdb\u884c\uff0c\u5e76\u4f69\u6234\u4e2a\u4eba\u9632\u62a4\u88c5\u5907\u3002<br \/>\n5. \u8d28\u91cf\u63a7\u5236\u4e0e\u5b89\u5168\u4fe1\u606f<br \/>\n\u672c\u4ea7\u54c1\u7ecfHPLC\u9a8c\u8bc1\uff0c\u7eaf\u5ea6\u226796%\u3002\u4f7f\u7528\u65f6\u9700\u6ce8\u610f\u4ee5\u4e0b\u5b89\u5168\u4fe1\u606f\uff1a<br \/>\n&#8211; \u907f\u514d\u76f4\u63a5\u63a5\u89e6\u76ae\u80a4\u6216\u773c\u775b\uff0c\u64cd\u4f5c\u65f6\u9700\u7a7f\u6234\u5b9e\u9a8c\u670d\u548c\u624b\u5957\u3002<br \/>\n&#8211; \u5982\u4e0d\u614e\u63a5\u89e6\uff0c\u7acb\u5373\u7528\u5927\u91cf\u6e05\u6c34\u51b2\u6d17\u5e76\u5c31\u533b\u3002<br \/>\n&#8211; \u672c\u54c1\u4ec5\u4f9b\u79d1\u7814\u4f7f\u7528\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u4f53\u6216\u4e34\u5e8a\u6cbb\u7597\u3002<br \/>\n&#8211; \u5e9f\u5f03\u5904\u7406\u9700\u7b26\u5408\u5f53\u5730\u6cd5\u89c4\uff0c\u907f\u514d\u73af\u5883\u6c61\u67d3\u3002<\/p>\n","protected":false},"featured_media":77353,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"product_category":[32],"class_list":["post-128930","chemical-product","type-chemical-product","status-publish","has-post-thumbnail","hentry","product_category-32"],"acf":[],"taxonomy_info":{"product_category":[{"value":32,"label":"\u751f\u5316\u8bd5\u5242"}]},"featured_image_src_large":["https:\/\/bio-get.com\/wp-content\/uploads\/2026\/04\/1207358-59-5.jpg",364,364,false],"author_info":[],"comment_info":"","_links":{"self":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product\/128930","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/chemical-product"}],"about":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/types\/chemical-product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=\/wp\/v2\/media\/77353"}],"wp:attachment":[{"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=128930"}],"wp:term":[{"taxonomy":"product_category","embeddable":true,"href":"https:\/\/bio-get.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_category&post=128930"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}